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Seth Berkley, former CEO of GAVI, the Vaccine Alliance, has written a new book — Fair Doses — that tells the inside story of the effort to expand access to vaccines, especially to low- and middle-income countries. Berkley also outlines a vision for how the globe might do better next time. Ben de la Cruz/NPR

Russell Crowe plays Hermann Goering, Hitler's second-in-command, in the latest on-screen portrayal of the Nuremberg trials. Nuremberg is in theaters now. Scott Garfield/Sony Pictures Classics hide caption toggle caption Scott Garfield/Sony Pictures Classics Russell Crowe and Rami Malek face off in an historical battle of wits and Weltanschauung in James Vanderbilt's new film Nuremberg. The

House Votes on Funding Bill, Shutdown Deal Dissent, COP30 Global Emissions Good morning. You're reading the Up First newsletter.  Subscribe  here to get it delivered to your inbox, and  listen  to the Up First podcast for all the news you need to start your day. Today's top story The U.S. Senate voted 60 to 40

Donated food items at Curley's House Food Bank in Miami, Florida, US, on Tuesday, Nov. 4, 2025. Eva Marie Uzcategui/Bloomberg/via Getty Images hide caption toggle caption Eva Marie Uzcategui/Bloomberg/via Getty Images When Kevin Curry graduated from Harvard Business School during the global recession in 2008, he couldn't find work. So he went to sign up

Sunnu Rebecca Choi for NPR Q: I just found out I'm pregnant. According to my period tracking app, I'm about five weeks along. But I can't get a first prenatal appointment until I'm nine weeks in. I'm super stressed out. Why can't I see a doctor sooner? And is it really OK to wait that

Back in the 1980s, a young economist — and future Nobel winner — named Richard Thaler began writing a series of columns that challenged the dominant doctrine of his field. At the time, most of the economics profession was smitten with a cartoonish picture of human behavior. A depiction of humans as selfish, smart, calculating

Pakistani security officials stand guard after a powerful car bomb exploded outside a district court in Islamabad, Pakistan, Tuesday, Nov. 11, 2025. Mohammad Yousuf/AP hide caption toggle caption Mohammad Yousuf/AP ISLAMABAD — A suicide bomber struck outside the gates of a district court in Islamabad on Tuesday, detonating his explosives next to a police car

President Donald Trump speaks during an event to announce new tariffs in the Rose Garden at the White House, Wednesday, April 2, 2025, in Washington. Mark Schiefelbein/AP hide caption toggle caption Mark Schiefelbein/AP President Trump has bragged many times about the revenue tariffs are bringing in – money paid by American businesses, who pass some

Combat medic Olena Ivanenko, 44, whose military call sign is "Ryzh," takes a break from the front line in the northeastern city of Sumy, Ukraine, earlier this year. Anton Shtuka for NPR hide caption toggle caption Anton Shtuka for NPR KYIV and KHARKIV, Ukraine — Maryna Mytsiuk spends her free time at a shooting range

At COP30, nations confront stalled action to address climate change Countries are gathering in Brazil at the COP30 summit to take stock of climate change. As in past summits, the negotiations are starting on the back foot: countries already aren't meeting their goals to cut heat-trapping emissions from burning fossil fuels. The world has barely