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Iran Deadline, Middle East War Escalation, Artemis II Trip Home Good morning. You're reading the Up First newsletter.  Subscribe  here to get it delivered to your inbox, and  listen  to the Up First podcast for all the news you need to start your day. Today's top stories In a press conference last night, President Trump

A man sits among buildings destroyed in a joint attack by Israel and the United States on April 6, 2026, in Tehran, Iran. Majid Saeedi/Getty Images Europe hide caption toggle caption Majid Saeedi/Getty Images Europe President Trump promised on Monday a "complete demolition" of every bridge and power plant in Iran if a deal is

A model economy in flowing water. Julian Frost for Planet Money: A Guide To The Economic Forces That Shape Your Life /NPR/WW Norton hide caption toggle caption Julian Frost for Planet Money: A Guide To The Economic Forces That Shape Your Life /NPR/WW Norton Just for you newsletter readers, we wanted to share a favorite

Loading... The Iran war has been catastrophic for global oil and gas supplies, sending prices soaring. Drivers are paying a steep price at the pump every time they fuel up. Now, a host of other unexpected shortages and price spikes are starting to pop up, which stand to affect people's lives and pocket books. In

Taiwan's main opposition party KMT chairperson Cheng Li-wun attends a press conference at the Taiwan Foreign Correspondents' Club in Taipei on March 23, 2026. I-Hwa Cheng/AFP via Getty Images hide caption toggle caption I-Hwa Cheng/AFP via Getty Images Taiwan's main opposition leader, Cheng Li-wun of the Kuomintang Party (KMT), arrived in China on Tuesday for

Misty Pipe (left) delivers a care package for a mom she recently supported through pregnancy, Britney WolfVoice. Pipe offers free doula care because Lame Deer — her hometown on the Northern Cheyenne Indian Reservation in Montana — is about 100 miles from the closest hospital that delivers babies. Katheryn Houghton/KFF Health News hide caption toggle

Jonathan Kitchen/Getty Images Artificial intelligence has arrived in the field of mental health. Large health systems and independent therapists alike have begun to adopt different AI tools to manage the delivery of mental health treatment. The speed of the adoption — alongside disturbing incidents of individuals using general-use AI chatbots with catastrophic consequences — is

Artemis II commander and NASA astronaut Reid Wiseman looks out one of the Orion spacecraft's main cabin windows at the moon ahead of the crew's lunar flyby. After successfully looping around the moon, the space capsule is now headed back toward Earth. NASA hide caption toggle caption NASA The four-astronaut crew of NASA's Artemis II

Trump repeats threat to bomb Iran's infrastructure if a deal isn't reached, strikes in the Middle East intensify as Trump's deadline looms, Artemis II crew heads home after historic moon mission.

At least three people were killed and 15 more injured in Russian drone attacks on the southern Ukrainian port city of Odesa on Monday morning, according to local authorities. Among those reported dead were a 30-year-old woman and her 2-year-old daughter, plus a 53-year-old woman, after a drone struck a multi-story residential building. "Law enforcement